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Nasdaq top and bottom performing stocks at about 03:45 p.m. EDT

BUZZ - Nasdaq top and bottom performing stocks at about 03:45 p.m. EDT Nasdaq 100 .NDX Top Performers Percent Change Dollar Tree Inc DLTR.OQ +7.2% Tesla Inc TSLA.OQ +4.3% Zscaler Inc ZS.OQ +3.1% Comcast Corp CMCSA.OQ +2.7% Amazon.com Inc AMZN.OQ +2.3% Bottom Performers Percent Change Copart Inc CPRT.OQ -6.6% Old Dominion Freight Line Inc ODFL.OQ -5.4% AstraZeneca PLC AZN.OQ -3.4% Super Micro Computer Inc SMCI.OQ -3.1% Vertex Pharmaceuticals Inc VRTX.OQ -2.6% The Nasdaq 100 .NDX lost 36.77 points
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Nasdaq top and bottom performing stocks at about 12:01 p.m. EDT

BUZZ - Nasdaq top and bottom performing stocks at about 12:01 p.m. EDT Nasdaq 100 .NDX Top Performers Percent Change Tesla Inc TSLA.OQ +3.2% Dollar Tree Inc DLTR.OQ +2.3% Amazon.com Inc AMZN.OQ +2.1% Comcast Corp CMCSA.OQ +1.6% Arm Holdings PLC ARM.OQ +1.2% Bottom Performers Percent Change Copart Inc CPRT.OQ -7.1% Old Dominion Freight Line Inc ODFL.OQ -6.8% AstraZeneca PLC AZN.OQ -3.5% Vertex Pharmaceuticals Inc VRTX.OQ -3.1% Regeneron Pharmaceuticals Inc REGN.OQ -3.0% The Nasdaq 100 .NDX lost 9
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Nasdaq top and bottom performing stocks at about 12:01 p.m. EDT

BUZZ - Nasdaq top and bottom performing stocks at about 12:01 p.m. EDT Nasdaq 100 .NDX Top Performers Percent Change Gilead Sciences Inc GILD.OQ +2.0% Vertex Pharmaceuticals Inc VRTX.OQ +1.8% Copart Inc CPRT.OQ +1.2% Verisk Analytics Inc VRSK.OQ +1.2% Old Dominion Freight Line Inc ODFL.OQ +1.1% Bottom Performers Percent Change Super Micro Computer Inc SMCI.OQ -25.1% PDD Holdings Inc PDD.OQ -6.3% Arm Holdings PLC ARM.OQ -5.5% Lululemon Athletica Inc LULU.OQ -4.4% Micron Technology Inc MU.OQ -4.3%
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Financial Times - Aug 8

PRESS DIGEST- Financial Times - Aug 8 Aug 8 (Reuters) - The following are the top stories in the Financial Times. Reuters has not verified these stories and does not vouch for their accuracy. Headlines - NHS in England to roll out 1.7 mln pound Crispr gene editing drug - Ministry of Defence asks suppliers to identify budget cuts - H2O Asset Management to pay investors 250 mln euros after FCA finds 'serious breaches' - UK signals move to curb overseas hiring for tech and engineering jobs Overview
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British Business - August 8

PRESS DIGEST-British Business - August 8 Aug 8 (Reuters) - The following are the top stories on the business pages of British newspapers. Reuters has not verified these stories and does not vouch for their accuracy. The Times - Asset manager H2O has agreed to pay out 250 million euros ($273.35 million) to investors who have been trapped since 2020 in illiquid funds linked to Lars Windhorst, the German financier.
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UK's NHS to roll out Vertex/CRISPR gene therapy for rare blood disorder

UPDATE 1-UK's NHS to roll out Vertex/CRISPR gene therapy for rare blood disorder Updates with details from statement in paragraphs 2-6, updates with background in paragraphs 7-8 Aug 7 (Reuters) - Britain's National Health Service (NHS) will begin to roll out a gene therapy from Vertex Pharmaceuticals VRTX.O and CRISPR Therapeutics CRSP.BN to treat rare blood disorder beta thalassemia, Vertex said in a statement on Wednesday.
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UK's NHS to roll out Vertex/CRISPR gene therapy for rare blood disorder

UPDATE 1-UK's NHS to roll out Vertex/CRISPR gene therapy for rare blood disorder Updates with details from statement in paragraphs 2-6, updates with background in paragraphs 7-8 Aug 7 (Reuters) - Britain's National Health Service (NHS) will begin to roll out a gene therapy from Vertex Pharmaceuticals VRTX.O and CRISPR Therapeutics CRSP.BN to treat rare blood disorder beta thalassemia, Vertex said in a statement on Wednesday.
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UK's NHS to roll out Vertex/CRISPR gene therapy for rare blood disorder

UK's NHS to roll out Vertex/CRISPR gene therapy for rare blood disorder Aug 7 (Reuters) - Britain's National Health Service(NHS) will begin rolling out Vertex Pharmaceuticals VRTX.O and CRISPR Therapeutics' CRSP.BN gene therapy to treat rare blood disorder beta thalassemia, Vertex said in a statement on Wednesday. Reporting by Gursimran Kaur in Ben
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Vertex Announces Casgevy Reimbursement Agreement For Treatment Of Transfusion-Dependent Beta Thalassemia In England

BRIEF-Vertex Announces Casgevy Reimbursement Agreement For Treatment Of Transfusion-Dependent Beta Thalassemia In England Aug 7 (Reuters) - Vertex Pharmaceuticals Inc VRTX.O : VERTEX ANNOUNCES CASGEVY™ REIMBURSEMENT AGREEMENT FOR THE TREATMENT OF TRANSFUSION-DEPENDENT BETA THALASSEMIA IN ENGLAND VERTEX PHARMACEUTICALS - ELIGIBLE TRANSFUSION-DEPEN
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US FDA approves Novartis' kidney disease drug

UPDATE 2-US FDA approves Novartis' kidney disease drug Adds background in paragraphs 6 to 10 By Sriparna Roy Aug 7 (Reuters) - The U.S. Food and Drug Administration has approved the use of Novartis' NOVN.S drug to reduce excess protein in the urine of patients with a type of kidney disease, the health regulator's website showed on Wednesday. The drug, Fabhalta, is already approved to treat adults with paroxysmal nocturnal hemoglobinuria, a rare blood disorder.
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U.S. Booking Holdings, Doordash, Vertex Pharmaceuticals

U.S. RESEARCH ROUNDUP- Booking Holdings, Doordash, Vertex Pharmaceuticals Aug 5 (Reuters) - Wall Street securities analysts revised their ratings and price targets on several U.S.-listed companies including Booking Holdings, Doordash and Vertex Pharmaceuticals, on Monday. HIGHLIGHTS * Academy Sports and Outdoors Inc ASO.O : JP Morgan cuts to neutral from overweight * Booking Holdings Inc BKNG.O : Jefferies cuts target price to $4350 from $4650 * Doordash DASH.O : D.A.
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US Q2 earnings growth estimate dips, reflecting Vertex loss, LSEG says

UPDATE 1-US Q2 earnings growth estimate dips, reflecting Vertex loss, LSEG says Updates with details on Vertex Pharmaceuticals By Caroline Valetkevitch NEW YORK, Aug 2 (Reuters) - The earnings growth estimate for S&P 500 .SPX companies for the second quarter dipped to 12.9% as of Friday from 13.3% on Thursday, according to LSEG data. The latest estimate is based on actual results from 376 of the S&P 500 companies and estimates for the rest.
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Vertex Pharma raises annual revenue forecast on strong demand for its cystic fibrosis treatments

Vertex Pharma raises annual revenue forecast on strong demand for its cystic fibrosis treatments Aug 1 (Reuters) - Vertex Pharmaceuticals VRTX.O raised its annual revenue forecast on Thursday, betting on robust demand for its cystic fibrosis (CF) treatments. The drugmaker now expects 2024 product revenue in the range of $10.65 to $10.85 billion, compared to its prior forecast of $10.55 to $10.75 billion.
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Vertex Pharmaceuticals Q2 Net Income 3,593.6 Million

BRIEF-Vertex Pharmaceuticals Q2 Net Income USD -3,593.6 Million Aug 01 (Reuters) - Vertex Pharmaceuticals Q2 revenue USD 2,645.6 million vs. IBES estimate USD 2,662 million. Q2 adjusted operating income USD -3,514.7 million vs. IBES estimate USD 1,243 million Q2 pretax profit USD -3,391.2 million vs. IBES estimate USD 1,345 million Q2 adjusted net income USD -3,593.6 million vs.
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Nasdaq top and bottom performing stocks at about 12:01 p.m. EDT

BUZZ - Nasdaq top and bottom performing stocks at about 12:01 p.m. EDT Nasdaq 100 .NDX Top Performers Percent Change Meta Platforms Inc META.OQ +6.1% Dexcom Inc DXCM.OQ +3.5% Cognizant Technology Solutions Corp CTSH.OQ +2.8% Vertex Pharmaceuticals Inc VRTX.OQ +1.8% AstraZeneca PLC AZN.OQ +1.4% Bottom Performers Percent Change Moderna Inc MRNA.OQ -19.5% Arm Holdings PLC ARM.OQ -16.0% Qualcomm Inc QCOM.OQ -8.7% Lam Research Corp LRCX.OQ -8.3% Micron Technology Inc MU.OQ -6.7% The Nasdaq 100 .NDX l
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What to Watch in the Day Ahead - Thursday, August 1

What to Watch in the Day Ahead - Thursday, August 1 The Day Ahead is an email and PDF publication that includes the day's major stories and events, analyses and other features. To receive The Day Ahead, Eikon users can register at DAY/US . Thomson One users can register at RT/DAY/US. All times in ET/GMT Apple is expected to report a rise in third-quarter revenue, helped by higher iPad sales from new launches and strength in its services business.
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Vertex Pharmaceuticals Inc <VRTX.OQ> expected to post earnings of $4.14 a share - Earnings Preview

Vertex Pharmaceuticals Inc expected to post earnings of $4.14 a share - Earnings Preview Vertex Pharmaceuticals Inc VRTX.OQ VRTX.O is expected to show a rise in quarterly revenue when it reports results on August 1 for the period ending June 30 2024 The Boston Massachusetts-based company is expected to report a 6.8% increase in revenue to $2.662 billion from $2.49 billion a year ago, according to the mean estimate from 23 analysts, based on LSEG data.
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Vertex: Genomics PLC Announces New Extension And Expansion Of Drug Discovery Collaboration With Co

BRIEF-Vertex: Genomics PLC Announces New Extension And Expansion Of Drug Discovery Collaboration With Co July 16 (Reuters) - Vertex Pharmaceuticals Inc VRTX.O : GENOMICS PLC ANNOUNCES NEW EXTENSION AND EXPANSION OF DRUG DISCOVERY COLLABORATION WITH VERTEX GENOMICS PLC - THREE-YEAR EXTENSION OF COLLABORATION TO USE GENOMICS TO ACCELERATE DRUG DISCOV
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Orum Therapeutics Anoounces Global, Multi-Target License, Option Agreement With Vertex For Use Of Orum's TPD Technology

BRIEF-Orum Therapeutics Anoounces Global, Multi-Target License, Option Agreement With Vertex For Use Of Orum's TPD Technology July 16 (Reuters) - Vertex Pharmaceuticals Inc VRTX.O : ORUM THERAPEUTICS-GLOBAL, MULTI-TARGET LICENSE, OPTION AGREEMENT WITH VERTEX FOR USE OF ORUM'S TPD² TECHNOLOGY TO DEVELOP DEGRADER-ANTIBODY CONJUGATES ORUM THERAPEUTIC
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Vertex sues US over fertility support program for Casgevy gene editing therapy

UPDATE 2-Vertex sues US over fertility support program for Casgevy gene editing therapy Adds OIG response July 15 (Reuters) - Vertex Pharmaceuticals VRTX.O sued the U.S. Department of Health and Human Services on Monday, seeking a court declaration that a fertility support program for patients who are prescribed its gene editing therapy Casgevy does not violate federal anti-kickback laws.
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